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Human sera and related serum-derived preparations are used in cell culture, immunoassays, and other laboratory research. Depending on the preparation, they may supplement culture media or serve as blocking reagents and assay controls.
A polyphenolic antioxidant that is abundant in many fruits vegetables plant bark and peels has anti-carcinogenic anti-mutagenic anti-inflammatory and organ-preserving properties blocks methylation of H3R17 by CARM1 without significantly altering histone acetylase or DNA methyltransferase activity
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A sesquiterpene lactone with anticancer activity inhibits the proliferation of MDA-MB-231 MDA-MB-468 and MCF-7 human breast cancer cells (IC50s 5.211 3.405 and 9.083 UM respectively after 48 hours) inhibits migration of MDA-MB-231 cells at 2.5 5 and 10 UM reduces tumor volume in an MDA-MB-231 orthotopic mouse xenograft model at 25 and 50 mg/kg
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An analytical reference standard that is structurally similar to known phytocannabinoids has been found in Cannabis intended for research and forensic applications
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Antgen purfed eggshell protens (Zrp and small amounts of zona pellucda protens) from Atlantc salmon (S salar) Host mouse clone MN2B4 CrossReactvty ( ) Atlantc salmon (S salar) (reacts prmarly wth B monomer) ranbow trout (O mykss) and Arctc char (S alpnus) Zrp Applcaton(s) WB and ELSA sotype gG1K
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A DNA alkylating agent active metabolite of dacarbazine (DTIC) active degradation product of temozolomide cytotoxic to L-cells and decreases thymidine and uridine uptake by 55 and 65 respectively at 1 mM cytotoxic to TLX5 murine lymphoma cells induces formation of mammary adenofibromas in rats when administered at a cumulative dose of 890 mg per animal over 14 weeks
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A cell-permeable benzoxazolo-sulfonamide compound that blocks human FBPase-1 enzymatic activity by competing at the AMP allosteric binding site (IC50 3 4 UM Ki 1 1 UM) blocks glucose production in starved rat hepatoma cells (IC50 6 6 UM)
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